Articles Posted in Defective Drugs

Recently, Tennessee injury lawyer Rick Piliponis was interviewed about the potential problems with Wellbutrin or bupropioin. Wellbutrin is a prescription drug medication that is used to treat depression. It appears that when this drug is taken during pregnancy it can increase the likelihood of several congenital defects. Specifically, it is believed that the drug can cause malformation of the child’s heart. The specific heart defect is known as hypoplastic left heart syndrome.

If you would like to learn more about these case you can watch Rick’s interview below:

https://www.youtube.com/watch?v=-cnKOoG5WyQ

In Tennessee and all over the United States, people have heard about several medications that may have severe or dangerous side effects. The drug Wellbutrin has been added to this list of medications because it has been connected to heart birth defects. If you or someone you love has taken Wellbutrin while pregnant and your child may have or has a heart birth defect as a result, then you should speak to a Tennessee Wellbutrin and personal injury lawyer as soon as possible. They will work with you and make sure you get the compensation you need for what you have been through.

According to research studies and findings, there were more than 12,700 babies born in the U.S. between 1997 to 2004. Mothers who took Wellbutrin or Bupropion in the early part of their pregnancy were at a higher risk of having babies with heart defects during this time period, than babies whose mothers did not take the medication. This defect affects blood flow from the heart’s left chamber to the rest of the body. According to the study, the most common type of this defect was a narrowing of the body’s main artery and this defect needs to be corrected with surgery.

As shown by data from 6,853 infants born with a major heart defect and 5,869 infants with no defect, those born with a heart defect had a 0.5 percent report of their mother having taken Wellbutrin before pregnancy or early in their pregnancy. Ten of those cases were left outflow tract heart defects. Guidelines from 2009 from the American Psychiatric Association and American College of Obstetricians and Gynecologists point out that psychotherapy may be a better form of treatment for depression in pregnant women with mild depression. However, pregnant women with more severe depression may need to continue medication.

Recent reports may show that antidepressant medicines may disrupt breast cancer treatments which can cause patients to get the cancer again and die from it. Also, in October, it was found that women taking some antidepressants during their pregnancy may be at a greater risk of having premature birth and having more babies in the intensive care unit.
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In Tennessee and across the country, people expect that when they take medicine for certain medical conditions or illnesses that it will make them feel better and that it is safe. Unfortunately, sometimes medications that people may take may increase their chances of developing other more serious and even dangerous medical conditions and illnesses. In a recent case, Susan Elfont, Bernadette Kalenkoski and Judy Mulderig claim that they took the drug Prempro developed by the company Pfizer Inc., for menopause and later developed breast cancer. According to the lawsuit, Elfont who is sixty-six and a former teacher, took Premarin and Provera which later were combined the two hormones into the Prempro pill for over two years before being diagnosed with breast cancer in 1997. Kalenkoski who is sixty-eight and a former nursing aide took Prempro for over four years and was diagnosed with breast cancer in 2002. Finally, Mulderig also sixty-eight and a retired teacher took Premarin and Provera for eleven years beginning in 1988.

During the trial, the jury found out that during the tree week trial of the drug, none of three women had a history of breast cancer in their family and it was determined by professionals that their use of the menopause drug was what led them to develop the cancer. Pfizer Inc has faced other lawsuits and settlements in the past due to the drug Prempro. This drug combined Premarin and Provera into the Prempro pill in 1995. The marketing of the drug reached over $2billion before a study in 2002 discovered that Prempro had links to breast cancer. The jury awarded $20 million in compensation to Elfont, $27.85 million to Kalenkoski and $24.75 million to Mulderig.
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When Christopher Trejo was sixteen he suffered from reaction known as Toxic Epidermal Necrolysis after taking Motrin as directed for less than one week. This reaction caused severe inside-out exfoliating damage affecting all of his mucosal membranes, which are like second- and third-degree burns over one hundred percent of his body. This reaction also caused severe pulmonary damage, near-blindness, infertility, whole-body scarring and hypoxic brain injury. Trejo’s abilities to hear, smell, see, taste, and touch have been severely reduced. This case was recently the subject of a dangerous drug lawsuit.

During the trial, the jury heard evidence that Motrin lacked adequate warnings about Stevens – Johnson syndrome and Toxic Epidermal Necrolysis, which have caused deaths and severe and permanent injuries to a several people who had used Motrin products. The jury also Motrin has been improperly labeled and should have been changed years ago to warn consumers about these and other severe reactions and side effects. The jury’s verdict of $48.2 million for general, special, and punitive damages against Johnson & Johnson as well as its fully owned subsidiary McNeil Consumer Healthcare is record setting.
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When Tennessee residents and people all over the United States go into a doctor’s office or hospital to have a medical procedure they expect to get better. Unfortunately, sometimes treatments or procedures are given that may be dangerous and harmful to patients and this may result in an injury and the need for additional care or treatment. If you or someone you love has had a procedure or taken medication and then suffered further injury as a result then you should talk to a Tennessee dangerous drug and personal injury attorney right away.

In this case, a man received Botox injections in 2007 as treatment for a hand tremor and writer’s cramp. The first two treatments went well, however after the third treatment the man suffered a rash then metal confusion that led to brain damage which left him disabled and needing twenty-four hour care. The Botox injections have left him unable to walk, talk, feed himself, or go to the bathroom. He has no health insurance and only receives Veteran Administration benefits.

According to the lawsuit which claims that Allergan, the producer of Botox, failed to warn his physician about the possible risks of Botox. According to evidence shown during the case, before July of 2007 Allergan sent letters to European doctors warning about the possible dangers of Botox but fail to disclose these warnings to doctors in the United States. This warnings included that Botox can spread beyond the injected muscle and cause severe auto-immune responses and brain injuries. Allergan instead of warning about these possible dangers stated that Botox was a miracle drug and compared to penicillin.

The Allergan Company in another settlement agreed to pay $600 million to the U.S. Justice Department when it illegally promoted the off-label use of Botox and encouraged doctors to use it for uses not approved by the Food and Drug Administration. In this case, the man was awarded $12 million in compensatory damages and $200 million in punitive damages.
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Once again we are hearing about another prescription drug that is doing more harm than good. This time it is Reglan, a drug prescribed to treat gastrointestinal disorders. Reports claim that it is responsible for a neurological disorder called tardive dyskinesia that causes uncontrolled movements and gestures such as lip smacking, jerking, grimacing or rapid eye blinking. Unfortunately there is no known treatment for the disorder and the conditions are rarely reversible. The FDA has begun requirements for stronger warning labels on the box in an attempt to better educate the public of the potential hazards of taking this drug.

Those at greatest risk appear to be infants, young children and the elderly. Even if the medicine is no longer being taken, tardive dyskinesia had been known to develop. The length of the prescription is supposed to be limited to three months or less and comes in tablet form as well as a liquid taken orally and as an injection.
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Over the last couple of years a growing trend in low impact thigh fractures has been seen. Many post-menopausal women here in Tennessee and across the nation taking the osteoporosis drug Fosamax have been experiencing painful and debilitating breaks in their femurs that are the result of simple everyday activities like stepping off a curb, going up a set of steps or falling from a standing height. Some had complained of a dull ache or persistent pain in their femurs or hips for a month or less before the fracture occurred.

A couple of years ago as these cases were beginning to come to light, the FDA requested an investigation into a possible link between bisphosphonate drugs and the fractures. Preliminary results were reported as there being no significant reason to believe that a connection existed but in March of 2010 the FDA requested that the American Society of Bone and Mineral Research (ASBMR) look into the matter and see what they could come up with. Their findings were significantly different than the original. Out of 310 spontaneous low impact fracture cases, it was found that 291 (94%) of the women had taken Fosamax or another bisphosphonate drug. Now the FDA has issued a new policy requiring that warnings of spontaneous low impact fractures be placed in the Warnings and Precautions section of their label.
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Many of us have seen commercials about the over the counter weight loss drug, Alli. Some of us have maybe even tried it or are still taking it. The Alli pill and program is supposed to change the way people think and feel about eating and dieting. It is has personalized plans and steps for each person and it is supposed to make burning calories even easier. Many of us across the country and even right here in Tennessee know about this pill, but many of us may not know the new problems it seems to be causing.

As of today, May 27, 2010, the Food and Drug Administration has revised the label for this drug so that includes new safety information about rare cases of severe liver injuries and damages. The FDA has not determined if Alli is actually causing the liver problems but wants the public to be aware because a condition like this is very serious.

This new warning is based on a complete review by the FDA of all data available from preclinical and clinical trials, as well as post marketing studies and the drug usage from April 1999 to August 7, 2009. The FDA has also identified thirteen post marketing cases of severe liver injury, twelve of them foreign cases involving another weight loss drug known as Xenical and one case involving Alli. In three of these cases, people needed liver transplants and two people died.

Even though cases like these are rare with this drug, it is unfortunate and sad when things like this happen, across the country and even right here in Tennessee. The FDA reported that about 40 million people worldwide use drugs like Xenical or Alli, which means that some of these cases could have been a friend or family member.
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Recently, the risk of zinc poisoning and exposure to denture cream products has lead to many pending lawsuits in Tennessee and across the country. It has also lead the company GlaxoSmithKline who manufactures, markets, and advertises for three zinc containing denture creams to stop manufacturing them as of February 18, 2010. These products are: Super Poligrip Original, Ultra Fresh and Extra Care. The company is now working on new formulas for the products that will not contain zinc. These should be available by mid April 2010.

A healthy amount of zinc is needed for everyone, but doctors have found that too much exposure to zinc with products like these denture creams can cause problems such as:
• Numbness and tingling • Lack of coordination for walking • Unusual sensations in the hands, arms, and legs • Weakness of arms and legs • Copper deficiency problems • Anemia • Bone Marrow Failure • Neuropathy (a condition that affects the nerves)

Some of these conditions are not that severe and when properly treated will not cause a person much more harm than some discomfort, but if zinc poisoning is misdiagnosed or untreated it can result in these more severe and life altering conditions and problems.

Many illnesses have some of these same symptoms, so it is important for doctors to test for zinc if you have taken a product containing zinc for a long period of time. Some of the conditions that have similar symptoms include:

• Demyelinating Syndrome • Multiple Sclerosis • Guillain-Barré Syndrome • Chronic Inflammatory Demyelinating Polyneuropath
If you or a loved one has used one of these products or similar denture cream products containing zinc, it is very important that you stop using the product, contact your doctor, and use a product that does not contain zinc instead. It is also important that you keep whatever records, products, or other information indicating what you have used. This is important in all defective products cases.
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Stomach sickness and a strange smell forced Johnson and Johnson (J&J) division McNeil Consumer Healthcare to finally recall from market a total of 27 products, including Tylenol, Benadryl, Rolaids and Motrin, their second recall this month. The company claims the recalled medicines, manufactured in a Puerto Rico plant, became tainted by the wood storage pallets where it was stored. Pallet manufacturers have openly and aggressively challenged this claim that chemical treatment 2,4,6-tribromoanisole (TBA) could, as J&J claims, permeate the boxes, packaging, and bottles to taint the recalled medication.

Moldy-smelling, musty bottles of Tylenol Arthritis Relief caplets were first reported 20 months ago, and since people have complained of digestive problems, including nausea, vomiting and stomach pain. Apparently FDA officials knew about the odor in 2008, having received over 100 complaints by August 2009, but only took critical action recently.

Kickbacks were the cause of a False Claims lawsuit against nursing home pharmaceutical provider Omnicare for which J&J was implicated. The $98 million settlement was based on allegations that the nursing home pharmacists were unnecessarily, and dangerously, prescribing nursing home residents with dementia the antipsychotic drug Risperdal. Unfortunate for the nursing home resident, Risperdal isn’t approved to treat agitated patients with dementia, but, according to the Justice Department (DOJ), this kickback scheme worked extremely well for J&J, tripling Omnicare’s sales of J&J drugs, from $100 million to $280 million with Risperdal making up $100 million of the latter sales figure.
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